FBCx & Weight Loss in Adults
The Beneficial Effects of FBCx on Blood Lipids & Weight Loss
FBCx is a soluble fiber derived from grain and is the primary ingredient in Calorease. It has been shown to form a stable complex with dietary fat. This complex is resistant to normal lipolytic hydrolysis by lipases and thereby reduces the absorption and bioavailability of dietary fat. In addition, the fiber-fat complex does not appear to be accessible to the human gut flora and therefore does not lead to the gastrointestinal side effects associated with weight loss products that cause fat malabsorption. The fiber-fat complex is then excreted in the stool intact. Other weight loss products that inhibit lipase secretion allow free, uncomplexed, dietary fats to pass through the digestive system, which may lead to steatorrhea (oily stool) and bowel incontinence.
It has previously been reported that early intervention with FBCx has beneficial effects on weight management, and that it preferentially reduces blood levels of saturated and trans fats. The current investigation involves overweight but not obese individuals and was intended to confirm the effects of FBCx on both weight management and improving blood lipid levels.
Forty-one healthy adults (age: 41.4 ± 13.6 years) participated in this 2-month, double-blinded, crossover study.
In 28 compliant participants (8 males and 20 females), when the active phase was compared to the control phase, there were significant decreases in body weight (−0.4 ± 0.2 kg, P < 0.05), serum total cholesterol (mean ± s.e.m., −0.295 ± 0.10 mmol/l, 5.3%, P < 0.02) and low-density lipoprotein (LDL) cholesterol (−0.23 ± 0.11 mmol/l, −6.7%, P < 0.05). Apolipoprotein B (Apo B) (−0.0404 ± 0.02 g/l, −5.6%, P = 0.06) and insulin levels also decreased by 9.5% (−0.16 ± 0.08 pmol/l, P = 0.06) while blood glucose and leptin levels did not change. These results suggest that FBCx exerts its beneficial health effects on body weight and blood lipid profile in healthy non-obese individuals.
Supplementation of 6 g/day of FBCx, the primary ingredient in Calorease, without any diet or lifestyle changes, induced weight loss, reduced atherogenic lipoproteins, and increased insulin sensitivity in healthy overweight individuals.